Brandon Moss might just make Boston miss him yet.

Moss homered among his three hits for the Oakland Athletics in Wednesday's 3-2 win and completed a three-game sweep of the Red Sox.

He finished 6 for 8 with five RBIs and three runs scored against his former club that traded him away.

''Playing against a team you came up with and team you played your first little bit in the big leagues is special,'' Moss said. ''You want to do well, not out of animosity, but to show, `Hey, you did draft a good player.'''

Jemile Weeks hit a go-ahead RBI single in the seventh following Coco Crisp's leadoff triple in Oakland's fourth straight win.

Red Sox slugger David Ortiz hit his 400th career home run and also scored on Adrian Gonzalez's sixth-inning single, but Boston couldn't avoid its first sweep by the A's since May 23-25, 2008, also in Oakland. The Red Sox lost just their fourth series in the past 17 and completed a disappointing 2-5 road trip through Seattle and Oakland, the AL West's two bottom teams.

''I wish he could celebrate,'' manager Bobby Valentine said. ''David is a team guy and he knows it's a great individual accomplishment, we all know that. But it's tarnished.''

Still, Ortiz returned to the clubhouse to some 40 congratulatory messages.

''And my phone is still blowing up,'' he said. ''I know at some point in my career when I'm not playing baseball I might look at it from the outside and be like, `Whoa, I guess I had a good career.' I look at it right now as just another home run.''

Moss homered leading off the second for his 10th of the season, giving the A's longballs in 15 straight games - most for the club since doing so in 17 in a row from April 12-May 1, 2002.

Moss singled in the fourth and doubled in the sixth, leaving him a triple shy of the cycle.

Brandon Inge doubled home Moss to tie the game at 2 in the sixth.