But his night was cut short, and he left after going 1 for 3 for 5 yards with one run for another 5 yards. After Cunningham drove his helmet into Vick's left side, the quarterback went down, got up slowly then knelt on one knee. He was checked by medical personnel before going to the sideline under his own power.
''That is just football,'' Cunningham said, ''going out there and getting the person with the ball.''
Foles, a rookie third-round draft pick from Arizona, came in and finished 18 for 28 for 217 yards and touchdown passes to Clay Harbor of 1 and 3 yards.
''He did a great job,'' McCoy said. ''In the huddle he demanded respect. He put everybody in the right places at the right times.''
McCoy scored on a 1-yard run, and Alex Henery kicked a 42-yard field goal to give the Eagles a 24-17 lead with 33 seconds left in the third quarter. He added a 21-yarder that capped the scoring with 2:00 remaining.
For the Patriots (1-1), third-stringer Ryan Mallett completed 10 of 20 passes for 105 yards, including a 7-yard scoring pass to Alex Silvestro. Brian Hoyer was just 5 for 17 for 55 yards.
''Ryan's a very confident player, both him and Brian,'' wide receiver Deion Branch said, ''but it's hard for them because they have to play behind Tom Brady.''
Stephen Gostkowski kicked field goals of 51, 35 and 55 yards for the Patriots, who have scored only two preseason touchdowns.
Vick's departure didn't change much for the Patriots despite his scrambling ability, defensive end Chandler Jones said.
''It's the same offensive scheme they're running,'' he said.
Vick wasn't the only first-stringer knocked out of the game. Philadelphia cornerback Dominique Rodgers-Cromartie and New England safety Patrick Chung went out in the first half with shoulder injuries. Mike Kafka, Vick's backup last year, missed the game with a hand injury.
The Patriots led 11-0 after Silvestro's touchdown 1:16 into the second quarter and a two-point conversion run by Shane Vereen. Then two lost fumbles within a span of six plays led to two Eagles touchdowns.