Novak Djokovic closed out his latest Wimbledon win with an ace, then threw a fist and let loose a primal scream.

Bring on Roger Federer. They'll meet at Wimbledon for the first time Friday.

Federer earned a record 32nd Grand Slam semifinal berth and moved closer to a record-tying seventh Wimbledon title when he beat Mikhail Youzhny on Wednesday, 6-1, 6-2, 6-2. Minutes later on an adjacent court, defending champion Djokovic finished off Florian Mayer, 6-4, 6-1, 6-4.

Federer has a 14-12 edge against Djokovic, who is ranked No. 1. They've met in Grand Slam semifinals five times in the past two years, with Djokovic winning four of those matches.

They've never played each other on grass.

''A nice matchup,'' Federer said. ''Obviously I'm aware that Novak is the defending champion and the world No. 1. That's not going to make it easy.''

''It's always a pleasure playing against Roger,'' Djokovic said. ''Obviously he's a great champion. He has been so dominant and consistent in these Grand Slams, and he's really an ultimate challenge on grass courts.''

Britain's Andy Murray reached his fourth straight Wimbledon semifinal Wednesday by rallying from a set and a break down to hold off David Ferrer of Spain 6-7 (5), 7-6 (6), 6-4, 7-6 (4).

Murray broke Ferrer when he served for the second set at 5-4 and then saved a set point at 6-5 in the tiebreaker to seize the momentum on Centre Court. The match was suspended for about 25 minutes at 5-5 in the fourth set, and Murray once again proved stronger in the tiebreaker when play resumed. He converted his first match point with an ace.

Murray will play Jo-Wilfried Tsonga, who reached the semis for the second straight year by beating Philipp Kohlschreiber.

Murray is trying to become the first British man to win Wimbledon since Fred Perry in 1936.